Its wide use within genome browsers has made it possible to define this format in a relatively stable way as this description is used by many tools. However, no official specifications were published at the time, which affected some formats such as FASTQ when sequencing projects multiplied at the beginning of the 21st century. Thus, many formats were created, such as FASTQ, GFF or BED. This required the sequencing centres to carry out major methodological development in order to automate the processing of sequences and their analyses. Among these projects, the Human Genome Project was the most ambitious at the time, aiming to sequence for the first time a genome of several gigabases. The end of the 20th century saw the emergence of the first projects to sequence complete genomes.
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June 2023
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